Set in Japan during the second world war, this is a story about personal responsibility and the effects of conscience. A team of doctors and nurses at a hospital of TB patients is faced with the opportunity to perform vivisections on American prisoners, in the interest of furthering medical science. Endo gives us the backgrounds of several of these characters, each of whom react differently to the horrific procedure. It was, apparently, one of the first times the issue of personal responsibility for actions taken during the war was brought up in Japanese fiction, and the novel won Endo awards and acclaim. It is a stark and stirring work, the clinical nature of the surgery scenes and the interior psychological wrestling of the characters in particular bearing the ring of truth.